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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3B All Species: 23.03
Human Site: T681 Identified Species: 38.97
UniProt: Q7Z3V4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7Z3V4 NP_569733.2 1068 123070 T681 S S A S P H V T H I T I R R S
Chimpanzee Pan troglodytes XP_509354 1068 122921 T681 S S A S P H V T H I T I R R S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543437 1068 123121 T681 S S A S P H V T H I T I R R S
Cat Felis silvestris
Mouse Mus musculus Q9ES34 1070 122743 T683 S S A S P H V T H I T I R R S
Rat Rattus norvegicus NP_001137366 1070 122598 T683 S S A S P H V T H I T I R R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423951 837 96057 E491 V N D L G V D E A G I D Q D G
Frog Xenopus laevis Q6DCL5 944 106566 S596 I L L V H R D S I F R S S C E
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 I419 I E V S R E E I F E E S Y R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 F650 P T N V P N K F E I R I R R T
Honey Bee Apis mellifera XP_392283 1063 121439 T677 A C N S T P T T L I V V H R T
Nematode Worm Caenorhab. elegans NP_499392 1066 120863 T683 L N D P Q M Q T W I T V Q R N
Sea Urchin Strong. purpuratus XP_786887 582 66877 D236 F I N E Q G L D E A G I D Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWB8 1029 117643 F664 S H G S Q G I F A R N R F R I
Baker's Yeast Sacchar. cerevisiae P53119 910 105547 L564 I I S R D N V L E D A F N A F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 N.A. 96.5 N.A. 92.1 91.8 N.A. N.A. 68.6 20.8 22.8 N.A. 20.4 51.5 37.6 37.1
Protein Similarity: 100 98.9 N.A. 98.5 N.A. 96 96.1 N.A. N.A. 74 40.1 38.4 N.A. 37.1 69.1 58.4 44.9
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 0 0 13.3 N.A. 33.3 26.6 26.6 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 13.3 6.6 13.3 N.A. 53.3 46.6 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. 28.7 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 48.7 42 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 36 0 0 0 0 0 15 8 8 0 0 8 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 15 0 8 0 15 8 0 8 0 8 8 8 8 % D
% Glu: 0 8 0 8 0 8 8 8 22 8 8 0 0 0 8 % E
% Phe: 8 0 0 0 0 0 0 15 8 8 0 8 8 0 8 % F
% Gly: 0 0 8 0 8 15 0 0 0 8 8 0 0 0 8 % G
% His: 0 8 0 0 8 36 0 0 36 0 0 0 8 0 0 % H
% Ile: 22 15 0 0 0 0 8 8 8 58 8 50 0 0 8 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 8 8 0 0 8 8 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 15 22 0 0 15 0 0 0 0 8 0 8 0 8 % N
% Pro: 8 0 0 8 43 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 22 0 8 0 0 0 0 0 15 8 8 % Q
% Arg: 0 0 0 8 8 8 0 0 0 8 15 8 43 72 0 % R
% Ser: 43 36 8 58 0 0 0 8 0 0 0 15 8 0 36 % S
% Thr: 0 8 0 0 8 0 8 50 0 0 43 0 0 0 15 % T
% Val: 8 0 8 15 0 8 43 0 0 0 8 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _